Upstate Animal Shelters and Animal Rescue Centers

Are you looking for animal shelters near Greenville, SC, or other animal welfare and rescue organizations upstate? Maybe you are looking to adopt a pet, or maybe you need to take care of your own pet or a stray that keeps coming to your home. One of the great things about our area is that there are several animal care facilities, animal shelters, and animal rescue organizations in Greenville and Spartanburg counties.

Every organization and facility works a little differently. Some have physical facilities, while others operate only as foster homes. We’ve compiled a list of animal shelters near Greenville, SC, as well as animal care facilities and rescue organizations in Spartanburg and upstate.

Animal shelters and care facilities in Greenville, SC

Carolina Loving Hound Rescue

Carolina Loving Hound Rescue exists to rescue, rehabilitate, rehoming or removing dogs. They provide medical and emotional rehabilitation to dogs in need.

Box 15288
Greenville, SC 29610

Animal-conscious citizens

Concerned Citizens for Animals (CCA) is the oldest no-kill shelter in upstate. Through their shelter operation in Simpsonville, a thrift store in Greenville, and a variety of community service programs, their goal is to provide a second chance to neglected, stray, and abandoned animals. They provide treatment, care and a safe haven for cats and dogs until they are adopted. They also offer low cost sterilization services. You can donate anything from clothing to household items, antiques to seasonal items, to the CCA Thrift Shop, and all proceeds go directly to CCA programs.

Thrift shop:
2425 New Easley Highway
Greenville, SC 29611

FootHills Golden Retriever Rescue, Inc.

FootHills Golden Retriever Rescue, Inc. is a full-service rescue service dedicated to providing needed rescue and veterinary care to unwanted, neglected, abused, homeless, and displaced golden retrievers. They work hard to find permanent homes for these dogs. They try to keep all available dogs in approved foster homes rather than a kennel.

Box 9077
Greenville, SC 29604

Greenville County Animal Care

It is the largest open admission pet store in South Carolina. They are dedicated to promoting the compassionate treatment of animals through adoption, education, and affordable veterinary and neuter care. They also accept lost pets from Greenville and Spartanburg counties.

328 Furman Hall Road
Greenville, SC 29609

Greenville Humane Society

The Greenville Humane Society exists to preserve life and improve animal welfare. They focus on finding homes for pets, but also offer other services such as vaccinations, spaying, and offering affordable flea, tick, and heartworm medications. You can get involved in several ways: donations, volunteering, promotion and organizing a fundraiser.

305 Airport Road
Greenville, SC 29607

Hugs for dogs

Hugs for Hounds is foster-based and has foster homes in SC, NC, NA, MD, DE, and NJ. They hold monthly adoption events in Midland Park, NJ.

Simpsonville, South Carolina
[email protected]

Long ear rescue

Long Ear Rescue is owned by Andrea and Jeff Durham who want to ensure that every donkey or mule is treated with love and respect. They provide sanctuary care for animals that cannot be rehomed, and they provide rescue, rehabilitation, and rehoming for eligible equines. They also provide food and veterinary assistance to equine owners who need temporary assistance.

Box 531
Greer, SC 29652

Lucky Puppy Rescue

Lucky Pup Rescue is a Greenville-based non-profit dog shelter committed to rescuing as many homeless dogs as possible and helping find forever homes for these puppies.

[email protected]

k9.5 Rescue

k9.5 Rescue is a home-based rescue organization in Greenville, SC dedicated to helping Great Pyrenees dogs, other giant breeds, seniors, and dogs with special needs. They focus on helping those most neglected in shelters due to their size, age, or need, and they provide medical, physical, behavioral, and emotional support to these dogs.


Rescued by Heart Pet Services

The goal of Saved with Heart is to keep pets with their families and in their homes. They educate pet owners about the many programs and services of other rescue agencies. They also house rescued pets with special needs.

Box 774
Greer, SC 29652

SC pet shelter

Pet Haven of South Carolina is a no-kill facility and exists to help preserve the life and well-being of all pets. They strive to not only strengthen the bond but also the understanding between animals and humans by providing a safe haven for abused and abandoned cats and dogs, with the goal of rehabilitating and adopting them into forever homes.


The Service Dog Institute

The Service Dog Institute knows firsthand that service dogs dramatically improve the lives of people with special needs, and their families. They exist to help raise and train service dogs, as well as train the handler and their families before placing service dogs into loving homes. They also offer ongoing support to these families.

655 Fairview Road H, #173
Simpsonville, SC 29680

Greenville Wildlife Rehabilitation

Wildlife Rehab of Greenville is dedicated to the rehabilitation and release of orphaned and injured wildlife. They also strive to educate the public.

If you find an animal in need, text (and include a photo if possible) or leave a message on their hotline at 864.233.0339.

Box 1801
Greenville, SC 29602

Spartanburg Animal Care and Rescue Facilities

animal allies

Animal Allies is a low cost spaying and neutering facility serving upstate and surrounding areas. They also offer vaccinations and other minor services. Their mission is to reduce the number of unwanted and unclaimed stray dogs and cats in our area.

820 Gosset Road
Spartanburg, SC 29307

Boykin Spaniel Rescue

Boykin Spaniel Rescue is an organization that helps ensure that every Boykin Spaniel who needs medical or emotional assistance not only gets the help they need, but is also placed in a forever home.

112 Hunter Ridge Drive
Boiling Springs, SC 29316

Paws Up Rescue and Resources

Paws Up is dedicated to keeping pets safe, happy and healthy while they wait to be placed in forever homes.

24 Oakwood Drive
Greenville, SC 29609

Pet Tender Angels Rescue and Rehabilitation

Pet Tender Angels Rescue and Rehabilitation offers dogs a place to find sanctuary, shelter and rehabilitation with the ultimate goal of being adopted into a loving family. Those interested in supporting their cause can volunteer, adopt, donate, or foster.

Box 273
Landrum, SC 29356

Spartanburg Humane Society

The Spartanburg Humane Society offers a variety of services focused on providing care to homeless animals in need. They offer adoption services and affordable veterinary care services such as neutering and vaccination services.

150 Dexter Road
Spartanburg, South Carolina

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